Basic Information
ID: ALA4371834
Type: Functional
Description: Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha-induced calcium flux by Fluo-4 NW or Calcium 4 dye based FLIPR TETRA assay
Format: BAO_0000219
Organism: Homo sapiens
Target: C-C chemokine receptor type 1(ALA2413)
Document: ALA4371017
Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha-induced calcium flux by Fluo-4 NW or Calcium 4 dye based FLIPR TETRA assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4371834
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.90 | 3.08 | 3.08 |
| 482.56 | 2.51 | 2.51 |
| 454.01 | 2.88 | 2.88 |
| 453.87 | 6.26 | 6.26 |
| 393.80 | 4.78 | 4.78 |
| 393.80 | 4.78 | 4.78 |
| 373.38 | 4.44 | 4.44 |
| 442.27 | 5.74 | 5.74 |
| 423.82 | 4.62 | 4.62 |
| 393.79 | 5.86 | 5.86 |
| 451.92 | 2.83 | 2.83 |
| 377.34 | 4.27 | 4.27 |
| 326.79 | 3.16 | 3.16 |
| 439.32 | 3.22 | 3.22 |
| 406.83 | 5.70 | 5.70 |
| 368.82 | 2.86 | 2.86 |
| 340.81 | 3.35 | 3.35 |
| 394.78 | 4.18 | 4.18 |
| 394.78 | 4.18 | 4.18 |
| 409.80 | 3.97 | 3.97 |
| 341.80 | 3.47 | 3.47 |
| 409.86 | 6.33 | 6.33 |
| 393.80 | 4.78 | 4.78 |
| 359.35 | 4.13 | 4.13 |
| 425.81 | 5.48 | 5.48 |
| 326.79 | 3.16 | 3.16 |
| 393.80 | 4.69 | 4.69 |
| 404.35 | 4.04 | 4.04 |
| 428.24 | 5.44 | 5.44 |
| 393.80 | 4.69 | 4.69 |
| 394.78 | 4.06 | 4.06 |
| 422.84 | 4.54 | 4.54 |
| 403.89 | 3.17 | 3.17 |
| 446.96 | 3.90 | 3.90 |
| 403.89 | 3.17 | 3.17 |
| 533.11 | 6.30 | 6.30 |
| 418.91 | 2.67 | 2.67 |
| 439.84 | 5.87 | 5.87 |
| 427.35 | 5.15 | 5.15 |
| 403.89 | 3.17 | 3.17 |
| 446.96 | 3.90 | 3.90 |
| 447.77 | 5.49 | 5.49 |
| 373.38 | 4.19 | 4.19 |
| 326.79 | 3.16 | 3.16 |
| 410.85 | 5.72 | 5.72 |
| 414.21 | 5.13 | 5.13 |