Basic Information
ID: ALA4371893
Type: Binding
Description: Inhibition of mouse GAT4 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels at 1 uM preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by microbeta liquid scintillation counting analysis
Format: BAO_0000219
Organism: Mus musculus
Target: GABA transporter 4(ALA3699)
Document: ALA4371022
Inhibition of mouse GAT4 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels at 1 uM preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by microbeta liquid scintillation counting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4371893
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.83 | 3.13 | 3.13 |
| 337.42 | 2.65 | 2.65 |
| 399.34 | 3.09 | 3.09 |
| 449.35 | 3.97 | 3.97 |
| 381.35 | 2.95 | 2.95 |
| 399.49 | 4.01 | 4.01 |
| 363.42 | 3.09 | 3.09 |
| 392.25 | 2.70 | 2.70 |
| 351.45 | 2.96 | 2.96 |
| 399.49 | 4.01 | 4.01 |
| 459.39 | 4.38 | 4.38 |
| 375.83 | 3.13 | 3.13 |
| 365.79 | 2.73 | 2.73 |
| 399.49 | 4.01 | 4.01 |
| 350.40 | 0.55 | 0.55 |
| 303.32 | 0.66 | 0.66 |