Basic Information
ID: ALA4371895
Type: Binding
Description: Inhibition of mouse GAT1 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by microbeta liquid scintillation counting analysis
Format: BAO_0000219
Organism: Mus musculus
Target: GABA transporter 1(ALA5445)
Document: ALA4371022
Inhibition of mouse GAT1 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by microbeta liquid scintillation counting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4371895
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.61 | 4.82 | 4.82 |
| 375.83 | 3.13 | 3.13 |
| 229.26 | 2.55 | 2.55 |