Basic Information
ID: ALA4371902
Type: Binding
Description: Inhibition of human GAT3 expressed in COS7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition and measured after 6 mins by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: GABA transporter 3(ALA5208)
Document: ALA4371022
Inhibition of human GAT3 expressed in COS7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition and measured after 6 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4371902
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.61 | 4.82 | 4.82 |
| 375.83 | 3.13 | 3.13 |
| 399.49 | 4.01 | 4.01 |
| 229.26 | 2.55 | 2.55 |