Assay Report Card

Basic Information

ID: ALA4372244

Type: Binding

Description: Inhibition of MT1-MMP-mediated proMMP-2 activation in human HT1080 cells stimulated with type I collagen for 24 hrs followed by compound addition assessed as increase in active MT1-MMP (55 KDa) level at 1 to 10 uM and measured after 24 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
388.471.501.50
1235.32