Basic Information
ID: ALA4372247
Type: Binding
Description: Inhibition of MT1-MMP-mediated proMMP-2 activation in human HT1080 cells stimulated with type I collagen for 24 hrs followed by compound addition assessed as increase in proMT1-MMP (65 KDa) level at 0.01 to 10 uM and measured after 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Matrix metalloproteinase 14(ALA3869)
Document: ALA4371035
Inhibition of MT1-MMP-mediated proMMP-2 activation in human HT1080 cells stimulated with type I collagen for 24 hrs followed by compound addition assessed as increase in proMT1-MMP (65 KDa) level at 0.01 to 10 uM and measured after 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4372247
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 567.62 | 3.25 | 3.25 |
| 1235.32 |