Basic Information
ID: ALA4372253
Type: Binding
Description: Inhibition of recombinant 6His-Tev-tagged LRRK2 (1326 to 2527) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-RLGRDKYKTLRQIRQGNTKQR-OH as substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs by TR-FRET assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4372253
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.34 | 5.07 | 5.07 |
| 403.49 | 3.06 | 3.06 |
| 404.47 | 3.53 | 3.53 |
| 388.47 | 4.30 | 4.30 |
| 374.44 | 3.91 | 3.91 |
| 404.47 | 3.27 | 3.27 |
| 405.80 | 6.19 | 6.19 |
| 447.54 | 3.08 | 3.08 |
| 396.40 | 3.76 | 3.76 |
| 407.34 | 5.81 | 5.81 |
| 390.44 | 3.14 | 3.14 |
| 372.35 | 4.93 | 4.93 |
| 378.41 | 3.47 | 3.47 |
| 402.50 | 4.12 | 4.12 |
| 413.48 | 4.05 | 4.05 |
| 416.48 | 3.39 | 3.39 |
| 415.50 | 3.06 | 3.06 |
| 389.46 | 2.72 | 2.72 |
| 446.55 | 4.13 | 4.13 |
| 406.46 | 4.25 | 4.25 |
| 414.36 | 5.55 | 5.55 |
| 373.33 | 4.33 | 4.33 |
| 418.50 | 3.52 | 3.52 |
| 423.79 | 6.33 | 6.33 |
| 418.50 | 3.92 | 3.92 |
| 443.55 | 3.84 | 3.84 |