Basic Information
ID: ALA4372258
Type: ADME
Description: Passive permeability across apical to basolateral side in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins in presence of P-gp inhibitor GF120918 by Transwell assay
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA4372258
permeability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.49 | 3.06 | 3.06 |
| 404.47 | 3.53 | 3.53 |
| 388.47 | 4.30 | 4.30 |
| 374.44 | 3.91 | 3.91 |
| 447.54 | 3.08 | 3.08 |
| 396.40 | 3.76 | 3.76 |
| 390.44 | 3.14 | 3.14 |
| 378.41 | 3.47 | 3.47 |
| 402.50 | 4.12 | 4.12 |
| 415.50 | 3.06 | 3.06 |
| 389.46 | 2.72 | 2.72 |
| 446.55 | 4.13 | 4.13 |
| 373.33 | 4.33 | 4.33 |
| 418.50 | 3.52 | 3.52 |
| 443.55 | 3.84 | 3.84 |