Basic Information
ID: ALA4372768
Type: Binding
Description: Inhibition of Plasmodium vivax C-terminal His6-tagged M1 aminopeptidase (195 to 1097 residues) expressed in Escherichia coli BL21(DE3) preincubated for 20 mins followed by L-leucine-7-amido-4-methylcoumarin addition by Morrison equation analysis
Organism: Plasmodium vivax
Activity Charts
Bioactivity
Activity Types for Assay ALA4372768
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.37 | 3.48 | 3.48 |
| 424.27 | 3.33 | 3.33 |
| 394.39 | 3.87 | 3.87 |
| 458.48 | 4.65 | 4.65 |
| 406.28 | 3.39 | 3.39 |
| 420.43 | 4.40 | 4.40 |
| 378.35 | 3.23 | 3.23 |
| 432.44 | 4.26 | 4.26 |
| 406.40 | 4.01 | 4.01 |
| 406.40 | 4.01 | 4.01 |
| 442.26 | 3.63 | 3.63 |
| 392.38 | 3.62 | 3.62 |
| 366.34 | 3.09 | 3.09 |
| 392.38 | 3.62 | 3.62 |
| 378.35 | 3.23 | 3.23 |
| 364.32 | 2.84 | 2.84 |
| 408.38 | 2.86 | 2.86 |
| 424.27 | 3.33 | 3.33 |
| 352.31 | 2.84 | 2.84 |