Basic Information
ID: ALA4372856
Type: Binding
Description: Inhibition of Wnt/beta-catenin signaling pathway in human SW480 cells cytosol lysate harboring APC mutation assessed as reduction in Axin2 protein expression at 5 uM after 18 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: SW480
Subcellular Fraction: Cytosol
Activity Charts
Bioactivity
Activity Types for Assay ALA4372856
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.12 | 3.86 | 3.86 |
| 351.15 | 4.06 | 4.06 |
| 339.70 | 4.52 | 4.52 |
| 316.70 | 3.41 | 3.41 |