Basic Information
ID: ALA4373125
Type: Functional
Description: Antiplasmodial activity against chloroquine-resistant asexual blood stage of Plasmodium falciparum K1 infected in human RBC assessed as reduction in [3H]hypoxanthine incorporation preincubated for 48 hrs followed by [3H]hypoxanthine addition measured after 24 hrs by liquid scintillation counting method
Format: BAO_0000218
Organism: Plasmodium falciparum
Strain: K1
Target: Plasmodium falciparum(ALA364)
Document: ALA4371072
Antiplasmodial activity against chloroquine-resistant asexual blood stage of Plasmodium falciparum K1 infected in human RBC assessed as reduction in [3H]hypoxanthine incorporation preincubated for 48 hrs followed by [3H]hypoxanthine addition measured after 24 hrs by liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4373125
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 384.43 | 2.60 | 2.60 |
| 385.35 | 3.61 | 3.61 |
| 513.33 | 5.70 | 5.70 |
| 441.26 | 6.36 | 6.36 |
| 453.23 | 6.44 | 6.44 |
| 453.23 | 6.44 | 6.44 |
| 367.33 | 4.39 | 4.39 |
| 425.20 | 5.89 | 5.89 |
| 411.31 | 6.15 | 6.15 |
| 453.23 | 6.44 | 6.44 |
| 436.32 | 6.02 | 6.02 |
| 436.32 | 6.02 | 6.02 |
| 468.36 | 5.12 | 5.12 |
| 384.34 | 5.13 | 5.13 |
| 569.27 | 6.38 | 6.38 |
| 436.32 | 6.02 | 6.02 |
| 453.23 | 6.44 | 6.44 |
| 450.34 | 5.89 | 5.89 |