Basic Information
ID: ALA4373201
Type: Binding
Description: Inhibition of Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a using Suc-LY-AMC as substrate preincubated for 10 mins followed by substrate addition and measured over 1 hr by fluorescence assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4373201
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 496.50 | 4.85 | 4.85 |
| 468.45 | 4.57 | 4.57 |
| 515.51 | 6.25 | 6.25 |
| 530.52 | 6.27 | 6.27 |
| 488.48 | 6.54 | 6.54 |
| 694.60 | 7.42 | 7.42 |
| 746.60 | 5.10 | 5.10 |
| 568.52 | 8.02 | 8.02 |
| 475.45 | 5.24 | 5.24 |
| 650.59 | 4.64 | 4.64 |
| 553.51 | 4.59 | 4.59 |
| 281.31 | 2.76 | 2.76 |
| 503.49 | 6.54 | 6.54 |
| 412.38 | 4.97 | 4.97 |
| 593.50 | 6.20 | 6.20 |
| 523.53 | 8.12 | 8.12 |
| 494.49 | 4.42 | 4.42 |
| 646.56 | 6.30 | 6.30 |
| 545.53 | 6.32 | 6.32 |
| 557.59 | 6.37 | 6.37 |
| 526.49 | 4.89 | 4.89 |
| 517.52 | 6.81 | 6.81 |
| 555.49 | 7.85 | 7.85 |
| 439.41 | 4.68 | 4.68 |
| 492.42 | 6.45 | 6.45 |
| 530.52 | 6.27 | 6.27 |
| 656.60 | 5.84 | 5.84 |
| 503.49 | 6.54 | 6.54 |
| 644.54 | 6.27 | 6.27 |
| 632.58 | 5.10 | 5.10 |
| 480.50 | 5.59 | 5.59 |
| 409.49 | 3.28 | 3.28 |
| 513.49 | 7.71 | 7.71 |
| 607.53 | 4.09 | 4.09 |
| 552.91 | 7.52 | 7.52 |
| 518.46 | 6.87 | 6.87 |
| 559.56 | 7.06 | 7.06 |
| 494.53 | 5.98 | 5.98 |
| 532.49 | 6.27 | 6.27 |
| 530.52 | 6.92 | 6.92 |
| 561.53 | 6.94 | 6.94 |
| 296.33 | 2.75 | 2.75 |
| 460.96 | 3.57 | 3.57 |
| 539.52 | 7.82 | 7.82 |
| 629.61 | 6.16 | 6.16 |
| 596.50 | 4.29 | 4.29 |
| 582.60 | 6.24 | 6.24 |
| 636.15 | 5.96 | 5.96 |
| 508.56 | 6.36 | 6.36 |
| 453.48 | 6.64 | 6.64 |
| 678.71 | 3.68 | 3.68 |
| 546.52 | 7.13 | 7.13 |
| 518.46 | 6.87 | 6.87 |
| 634.50 | 6.83 | 6.83 |
| 578.43 | 7.24 | 7.24 |
| 565.57 | 7.40 | 7.40 |
| 485.54 | 6.73 | 6.73 |
| 516.53 | 7.03 | 7.03 |
| 594.63 | 6.59 | 6.59 |
| 441.42 | 5.11 | 5.11 |
| 620.47 | 6.96 | 6.96 |
| 727.64 | 4.25 | 4.25 |
| 498.48 | 6.83 | 6.83 |
| 505.48 | 6.97 | 6.97 |
| 964.54 | 9.70 | 9.70 |
| 676.59 | 4.83 | 4.83 |
| 517.47 | 6.69 | 6.69 |
| 686.65 | 4.27 | 4.27 |
| 566.59 | 8.18 | 8.18 |
| 508.43 | 6.69 | 6.69 |
| 651.45 | 5.22 | 5.22 |
| 567.54 | 5.26 | 5.26 |
| 427.39 | 4.45 | 4.45 |
| 560.55 | 4.17 | 4.17 |
| 474.45 | 6.36 | 6.36 |
| 707.64 | 4.84 | 4.84 |
| 508.39 | 5.89 | 5.89 |
| 516.53 | 6.81 | 6.81 |
| 479.39 | 6.28 | 6.28 |
| 609.64 | 6.40 | 6.40 |
| 552.45 | 3.39 | 3.39 |
| 520.53 | 5.35 | 5.35 |
| 518.51 | 6.42 | 6.42 |
| 537.55 | 7.99 | 7.99 |
| 411.39 | 5.61 | 5.61 |
| 616.65 | 7.07 | 7.07 |
| 546.95 | 8.10 | 8.10 |
| 573.59 | 6.93 | 6.93 |
| 536.55 | 5.32 | 5.32 |
| 488.48 | 6.54 | 6.54 |
| 531.51 | 6.45 | 6.45 |
| 487.49 | 6.83 | 6.83 |
| 669.59 | 7.77 | 7.77 |
| 604.55 | 6.34 | 6.34 |
| 504.48 | 6.37 | 6.37 |
| 501.52 | 7.14 | 7.14 |
| 602.58 | 6.46 | 6.46 |
| 523.53 | 8.12 | 8.12 |
| 628.50 | 7.19 | 7.19 |
| 501.52 | 7.22 | 7.22 |
| 439.41 | 4.68 | 4.68 |
| 517.52 | 6.84 | 6.84 |
| 538.54 | 7.70 | 7.70 |
| 280.33 | 3.05 | 3.05 |
| 584.49 | 7.46 | 7.46 |
| 601.60 | 6.75 | 6.75 |