Basic Information
ID: ALA4373221
Type: Binding
Description: Inhibition of recombinant human Nav1.7 expressed in HEK293 cells at -70 mV holding potential by patch clamp electrophysiology method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Sodium channel protein type IX alpha subunit(ALA4296)
Document: ALA4371076
Inhibition of recombinant human Nav1.7 expressed in HEK293 cells at -70 mV holding potential by patch clamp electrophysiology method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4373221
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.43 | 4.14 | 4.14 |
| 435.93 | 3.62 | 3.62 |
| 436.92 | 3.01 | 3.01 |
| 459.96 | 3.90 | 3.90 |
| 445.52 | 3.64 | 3.64 |
| 440.42 | 4.23 | 4.23 |
| 414.38 | 3.69 | 3.69 |
| 479.96 | 4.29 | 4.29 |
| 446.50 | 3.03 | 3.03 |
| 384.50 | 3.73 | 3.73 |
| 453.92 | 3.76 | 3.76 |
| 441.41 | 3.62 | 3.62 |
| 422.43 | 4.09 | 4.09 |
| 419.48 | 3.10 | 3.10 |
| 396.39 | 3.55 | 3.55 |