Basic Information
ID: ALA4373339
Type: Binding
Description: Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Solute carrier family 22 member 12(ALA6120)
Document: ALA4371083
Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4373339
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.29 | 4.24 | 4.24 |
| 637.30 | 5.91 | 5.91 |
| 638.19 | 6.20 | 6.20 |
| 587.29 | 5.03 | 5.03 |
| 479.13 | 4.18 | 4.18 |
| 648.20 | 5.65 | 5.65 |
| 492.22 | 3.34 | 3.34 |
| 603.75 | 5.54 | 5.54 |
| 472.16 | 3.60 | 3.60 |
| 727.10 | 6.42 | 6.42 |
| 637.30 | 5.91 | 5.91 |
| 568.32 | 5.50 | 5.50 |
| 569.30 | 4.89 | 4.89 |
| 695.20 | 5.50 | 5.50 |
| 648.20 | 5.65 | 5.65 |
| 638.19 | 6.20 | 6.20 |
| 503.16 | 3.81 | 3.81 |
| 515.18 | 3.94 | 3.94 |
| 599.33 | 4.90 | 4.90 |
| 603.75 | 5.54 | 5.54 |
| 663.03 | 7.53 | 7.53 |