Basic Information
ID: ALA4373344
Type: Functional
Description: Positive allosteric modulation of Gqi5-fused human M4 AChR assessed as increase in acetylcholine-induced calcium mobilization
Format: BAO_0000357
Organism: Homo sapiens
Target: Muscarinic acetylcholine receptor M4(ALA1821)
Document: ALA4371085
Positive allosteric modulation of Gqi5-fused human M4 AChR assessed as increase in acetylcholine-induced calcium mobilization: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4373344
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.44 | 3.43 | 3.43 |
| 360.41 | 2.97 | 2.97 |
| 356.88 | 5.07 | 5.07 |
| 386.91 | 5.07 | 5.07 |
| 340.45 | 4.16 | 4.16 |
| 356.52 | 4.87 | 4.87 |
| 298.37 | 3.99 | 3.99 |
| 317.42 | 2.79 | 2.79 |
| 359.43 | 3.69 | 3.69 |
| 326.40 | 4.54 | 4.54 |
| 338.44 | 4.41 | 4.41 |
| 381.46 | 3.58 | 3.58 |
| 385.46 | 4.26 | 4.26 |
| 368.46 | 3.92 | 3.92 |
| 353.45 | 3.82 | 3.82 |
| 373.45 | 3.95 | 3.95 |
| 320.85 | 4.28 | 4.28 |
| 374.87 | 5.20 | 5.20 |
| 388.51 | 3.56 | 3.56 |
| 300.43 | 4.39 | 4.39 |
| 394.42 | 5.05 | 5.05 |
| 326.42 | 3.85 | 3.85 |
| 345.40 | 3.39 | 3.39 |
| 402.54 | 3.81 | 3.81 |
| 303.39 | 2.31 | 2.31 |
| 308.41 | 4.40 | 4.40 |
| 419.51 | 3.35 | 3.35 |
| 272.38 | 3.61 | 3.61 |
| 352.46 | 4.09 | 4.09 |
| 346.84 | 4.66 | 4.66 |
| 313.39 | 3.40 | 3.40 |
| 287.39 | 3.02 | 3.02 |