Agonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha16 assessed as reduction in forsklin-induced cAMP production incubate...

Basic Information

ID: ALA4374199

Type: ADME

Description: Agonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha16 assessed as reduction in forsklin-induced cAMP production incubated for 30 mins by cAMP Hunter assay based fluorometric analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target: Cannabinoid CB1 receptor(ALA218)

Document: ALA4373651

Agonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha16 assessed as reduction in forsklin-induced cAMP production incubated for 30 mins by cAMP Hunter assay based fluorometric analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4374199

EC50

Total(57)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
447.36	4.83	4.83
385.51	2.36	2.36
359.45	2.24	2.24
373.47	2.49	2.49
496.23	5.58	5.58
465.55	2.88	2.88
387.50	2.98	2.98
435.33	4.96	4.96
385.51	2.46	2.46
371.48	2.90	2.90
434.38	3.11	3.11
389.93	3.10	3.10
417.98	3.93	3.93
373.47	2.49	2.49
359.45	3.03	3.03
413.56	3.28	3.28
385.51	2.46	2.46
371.48	2.11	2.11
403.95	3.54	3.54
387.50	3.02	3.02
401.53	3.41	3.41
420.35	2.87	2.87
399.54	2.85	2.85
469.97	3.52	3.52
448.41	3.60	3.60
399.54	2.89	2.89
371.48	2.11	2.11
385.51	2.36	2.36
387.50	3.02	3.02
387.50	2.98	2.98
403.95	3.54	3.54
462.43	4.04	4.04
373.47	2.59	2.59
453.51	3.01	3.01
434.38	3.21	3.21
453.51	3.01	3.01
514.42	3.63	3.63
448.41	3.65	3.65
451.78	5.47	5.47
403.95	3.49	3.49
420.35	3.65	3.65
417.98	3.93	3.93
373.47	2.59	2.59
389.93	3.00	3.00
375.90	3.54	3.54
375.90	2.76	2.76
403.95	3.49	3.49
375.90	2.76	2.76
465.55	2.88	2.88
413.56	3.28	3.28
399.54	2.89	2.89
399.54	2.85	2.85
389.93	3.10	3.10
469.97	3.52	3.52
359.45	2.24	2.24
389.93	3.00	3.00
401.53	3.41	3.41