Basic Information
ID: ALA4374266
Type: Toxicity
Description: Therapeutic index, ratio of CC50 for cytotoxicity against human Hep2 cells to EC50 for antiviral activity against Respiratory syncytial virus Long infected in HEp-2 cells
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4373654
Therapeutic index, ratio of CC50 for cytotoxicity against human Hep2 cells to EC50 for antiviral activity against Respiratory syncytial virus Long infected in HEp-2 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4374266
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.96 | 4.04 | 4.04 |
| 429.93 | 3.31 | 3.31 |
| 443.96 | 3.70 | 3.70 |
| 457.98 | 4.09 | 4.09 |
| 430.92 | 2.71 | 2.71 |
| 430.92 | 2.71 | 2.71 |
| 409.51 | 2.97 | 2.97 |
| 429.93 | 3.31 | 3.31 |
| 423.54 | 3.22 | 3.22 |
| 413.47 | 2.80 | 2.80 |
| 425.51 | 2.67 | 2.67 |
| 474.38 | 3.42 | 3.42 |
| 430.92 | 2.71 | 2.71 |
| 457.98 | 4.09 | 4.09 |
| 420.49 | 2.53 | 2.53 |
| 463.48 | 3.68 | 3.68 |
| 443.96 | 3.70 | 3.70 |
| 395.48 | 2.66 | 2.66 |
| 429.93 | 3.31 | 3.31 |
| 441.94 | 3.63 | 3.63 |
| 429.93 | 3.31 | 3.31 |
| 428.95 | 3.94 | 3.94 |
| 441.94 | 3.63 | 3.63 |
| 442.97 | 4.33 | 4.33 |
| 429.93 | 3.31 | 3.31 |
| 429.93 | 3.31 | 3.31 |