Assay Report Card

Basic Information

ID: ALA4374303

Type: Binding

Description: Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as IKZF1 degradation by measuring IKZF1/tubulin ratio at 1 uM after 16 hrs by Western blot analysis relative to tubulin

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
273.25-0.33-0.33
608.743.043.04
580.682.262.26
624.742.272.27
636.793.823.82
652.793.053.05