Basic Information
ID: ALA4374366
Type: Functional
Description: Neuroprotective activity against OGD-induced neurotoxicity in Sprague-Dawley rat cortical neuron assessed as cell survival rate at 10 uM pretreated for 24 hrs followed by incubation in oxygen and glucose deprivation medium for 2 hrs followed by exposure to reoxygenation by re-incubating in normoxia condition for 24 hrs by MTT assay (Rvb = 58.5 to 61.2 %)
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Cell type: Cortical neurone
Activity Charts
Bioactivity
Activity Types for Assay ALA4374366
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 536.42 | 2.91 | 2.91 |
| 223.23 | -0.27 | -0.27 |
| 496.48 | 2.67 | 2.67 |
| 541.48 | 2.58 | 2.58 |
| 536.42 | 2.91 | 2.91 |
| 510.51 | 2.98 | 2.98 |
| 502.87 | 2.55 | 2.55 |
| 482.45 | 2.20 | 2.20 |
| 498.45 | 1.90 | 1.90 |
| 513.42 | 1.80 | 1.80 |
| 564.48 | 3.69 | 3.69 |
| 514.47 | 2.81 | 2.81 |
| 564.48 | 3.69 | 3.69 |
| 482.45 | 2.20 | 2.20 |
| 468.43 | 1.90 | 1.90 |
| 510.51 | 2.98 | 2.98 |
| 526.51 | 2.68 | 2.68 |
| 486.42 | 2.03 | 2.03 |
| 530.92 | 3.33 | 3.33 |