Basic Information
ID: ALA4374440
Type: Binding
Description: Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4374440
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 652.91 | 3.90 | 3.90 |
| 677.63 | 3.83 | 3.83 |
| 419.57 | 3.76 | 3.76 |
| 721.80 | 3.65 | 3.65 |
| 687.74 | 2.38 | 2.38 |
| 850.34 | 3.88 | 3.88 |
| 735.83 | 4.11 | 4.11 |
| 737.82 | 2.18 | 2.18 |
| 702.88 | 0.14 | 0.14 |
| 785.87 | 3.22 | 3.22 |
| 749.86 | 3.98 | 3.98 |
| 735.83 | 3.73 | 3.73 |
| 875.86 | 3.04 | 3.04 |
| 761.87 | 4.57 | 4.57 |
| 791.89 | 4.38 | 4.38 |
| 803.86 | 3.36 | 3.36 |
| 661.83 | -0.13 | -0.13 |
| 820.31 | 3.87 | 3.87 |
| 803.86 | 3.36 | 3.36 |
| 827.95 | 4.15 | 4.15 |