Basic Information
ID: ALA4374583
Type: Functional
Description: DNA alkylating activity in human A549 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: DNA(ALA2311221)
Document: ALA4373672
DNA alkylating activity in human A549 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4374583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.82 | 2.54 | 2.54 |
| 942.38 | 0.63 | 0.63 |