DNA alkylating activity in human MCF7 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability...

Basic Information

ID: ALA4374584

Type: Functional

Description: DNA alkylating activity in human MCF7 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: MCF7

Target: DNA(ALA2311221)

Document: ALA4373672

DNA alkylating activity in human MCF7 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4374584

IC50

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
384.82	2.54	2.54
942.38	0.63	0.63

Parent Molecular Weight

ALogP

Polar Surface Area

384.82

2.54

942.38

0.63

DNA alkylating activity in human MCF7 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability...

Basic Information

Activity Charts

Compound Summary