Basic Information
ID: ALA4374589
Type: Functional
Description: DNA alkylating activity in GCPII negative human PC3 cells exhibiting increased cathepsin B activity assessed as reduction in cell viability incubated with GCPII binder 2-PMPA for 1 hr followed by incubation with compound for 48 hrs by MTS assay
Format: BAO_0000019
Organism: Homo sapiens
Target: DNA(ALA2311221)
Document: ALA4373672
DNA alkylating activity in GCPII negative human PC3 cells exhibiting increased cathepsin B activity assessed as reduction in cell viability incubated with GCPII binder 2-PMPA for 1 hr followed by incubation with compound for 48 hrs by MTS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4374589
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.82 | 2.54 | 2.54 |
| 942.38 | 0.63 | 0.63 |