Basic Information
ID: ALA4374590
Type: Functional
Description: DNA alkylating activity in human LNCAP cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated with GCPII binder 2-PMPA for 1 hr followed by incubation with compound for 48 hrs by MTS assay
Organism: Homo sapiens
Cell type: LNCaP
Activity Charts
Bioactivity
Activity Types for Assay ALA4374590
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.82 | 2.54 | 2.54 |
| 942.38 | 0.63 | 0.63 |