Basic Information
ID: ALA4374800
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis LeuRS expressed in Escherichia coli Rosetta (DE3) cells at 100 uM incubated for 30 mins followed by incubation with ATP, leucine, tRNA, iPPase for 10 mins and measured after 30 mins by BIOMOL Green reagent based plate reader analysis relative to control
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA4374800
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 305.36 | 2.78 | 2.78 |
| 414.28 | 3.55 | 3.55 |
| 289.36 | 3.07 | 3.07 |
| 262.29 | 2.81 | 2.81 |
| 322.44 | 4.32 | 4.32 |
| 312.19 | 3.36 | 3.36 |
| 352.42 | 4.73 | 4.73 |
| 261.31 | 2.60 | 2.60 |
| 277.35 | 2.91 | 2.91 |
| 303.39 | 3.50 | 3.50 |
| 392.27 | 5.26 | 5.26 |
| 416.46 | 5.96 | 5.96 |
| 340.36 | 3.87 | 3.87 |
| 340.41 | 3.67 | 3.67 |
| 449.29 | 4.64 | 4.64 |
| 406.28 | 5.17 | 5.17 |
| 319.34 | 2.38 | 2.38 |
| 422.29 | 5.12 | 5.12 |
| 418.32 | 4.94 | 4.94 |
| 373.87 | 4.83 | 4.83 |
| 415.39 | 3.79 | 3.79 |
| 248.27 | 2.50 | 2.50 |
| 333.37 | 2.39 | 2.39 |
| 261.35 | 3.21 | 3.21 |
| 333.37 | 2.77 | 2.77 |
| 403.26 | 4.93 | 4.93 |
| 354.23 | 3.45 | 3.45 |
| 320.33 | 2.59 | 2.59 |
| 312.19 | 3.37 | 3.37 |
| 463.15 | 4.30 | 4.30 |
| 357.36 | 4.09 | 4.09 |
| 368.26 | 3.84 | 3.84 |
| 429.93 | 5.34 | 5.34 |
| 333.46 | 4.56 | 4.56 |
| 295.37 | 3.96 | 3.96 |
| 368.26 | 3.84 | 3.84 |
| 309.39 | 4.27 | 4.27 |