Basic Information
ID: ALA4374801
Type: Binding
Description: Inhibition of recombinant Mycobacterium tuberculosis H37Rv C-terminal His6-tagged MetRS expressed in Escherichia coli BL21 (DE3) Star cells at 100 uM incubated for 30 mins followed by incubation with ATP, methionine, tRNA, iPPase for 10 mins and measured after 30 mins by BIOMOL Green reagent based plate reader analysis relative to control
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA4374801
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 305.36 | 2.78 | 2.78 |
| 414.28 | 3.55 | 3.55 |
| 289.36 | 3.07 | 3.07 |
| 262.29 | 2.81 | 2.81 |
| 322.44 | 4.32 | 4.32 |
| 312.19 | 3.36 | 3.36 |
| 352.42 | 4.73 | 4.73 |
| 261.31 | 2.60 | 2.60 |
| 277.35 | 2.91 | 2.91 |
| 303.39 | 3.50 | 3.50 |
| 392.27 | 5.26 | 5.26 |
| 416.46 | 5.96 | 5.96 |
| 340.36 | 3.87 | 3.87 |
| 340.41 | 3.67 | 3.67 |
| 449.29 | 4.64 | 4.64 |
| 406.28 | 5.17 | 5.17 |
| 319.34 | 2.38 | 2.38 |
| 422.29 | 5.12 | 5.12 |
| 418.32 | 4.94 | 4.94 |
| 373.87 | 4.83 | 4.83 |
| 415.39 | 3.79 | 3.79 |
| 248.27 | 2.50 | 2.50 |
| 333.37 | 2.39 | 2.39 |
| 261.35 | 3.21 | 3.21 |
| 333.37 | 2.77 | 2.77 |
| 403.26 | 4.93 | 4.93 |
| 354.23 | 3.45 | 3.45 |
| 320.33 | 2.59 | 2.59 |
| 312.19 | 3.37 | 3.37 |
| 463.15 | 4.30 | 4.30 |
| 357.36 | 4.09 | 4.09 |
| 368.26 | 3.84 | 3.84 |
| 429.93 | 5.34 | 5.34 |
| 333.46 | 4.56 | 4.56 |
| 295.37 | 3.96 | 3.96 |
| 368.26 | 3.84 | 3.84 |
| 309.39 | 4.27 | 4.27 |