Basic Information
ID: ALA4374803
Type: Binding
Description: Inhibition of recombinant Mycobacterium tuberculosis H37Rv C-terminal His6-tagged MetRS expressed in Escherichia coli BL21 (DE3) Star cells incubated for 30 mins followed by incubation with ATP, methionine, tRNA, iPPase for 10 mins and measured after 30 mins by BIOMOL Green reagent based plate reader analysis
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA4374803
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.26 | 5.02 | 5.02 |
| 326.22 | 3.67 | 3.67 |
| 296.19 | 3.66 | 3.66 |
| 392.27 | 5.26 | 5.26 |
| 406.28 | 5.17 | 5.17 |
| 415.39 | 3.79 | 3.79 |
| 403.26 | 4.93 | 4.93 |