Basic Information
ID: ALA4374938
Type: Binding
Description: Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 15 uM acetyl coenzyme A and N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin) as substrate incubated for 60 mins by Alpha screen technology
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4374938
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.38 | 2.17 | 2.17 |
| 398.48 | 3.64 | 3.64 |
| 344.37 | 2.60 | 2.60 |
| 356.40 | 2.47 | 2.47 |
| 360.82 | 3.12 | 3.12 |
| 372.42 | 3.16 | 3.16 |
| 362.36 | 2.74 | 2.74 |
| 360.82 | 3.12 | 3.12 |
| 344.37 | 2.60 | 2.60 |
| 360.82 | 3.12 | 3.12 |
| 340.40 | 2.77 | 2.77 |
| 344.37 | 2.60 | 2.60 |
| 351.39 | 2.33 | 2.33 |
| 342.38 | 1.50 | 1.50 |
| 378.81 | 3.26 | 3.26 |
| 368.46 | 3.59 | 3.59 |
| 412.36 | 3.62 | 3.62 |
| 358.39 | 2.91 | 2.91 |
| 326.38 | 2.46 | 2.46 |
| 356.40 | 2.47 | 2.47 |
| 410.37 | 3.36 | 3.36 |
| 341.39 | 2.05 | 2.05 |
| 441.51 | 3.81 | 3.81 |
| 340.40 | 2.77 | 2.77 |
| 340.40 | 2.77 | 2.77 |
| 358.39 | 2.91 | 2.91 |
| 368.41 | 2.67 | 2.67 |
| 402.48 | 4.13 | 4.13 |
| 351.39 | 2.33 | 2.33 |
| 342.38 | 2.17 | 2.17 |