Basic Information
ID: ALA4374960
Type: ADME
Description: Inhibition of human C-terminal His/FLAG-tagged ACE-2 expressed in HEK293 cells at 100 uM preincubated for 10 mins followed by Mca-Ala-Pro-Lys(Dnp)-OH substrate addition by fluorescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Angiotensin-converting enzyme 2(ALA3736)
Document: ALA4373692
Inhibition of human C-terminal His/FLAG-tagged ACE-2 expressed in HEK293 cells at 100 uM preincubated for 10 mins followed by Mca-Ala-Pro-Lys(Dnp)-OH substrate addition by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4374960
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 219.12 | ||
| 307.18 | ||
| 303.19 | ||
| 219.12 | ||
| 177.03 | ||
| 303.19 | ||
| 343.26 | ||
| 271.12 | ||
| 267.16 | ||
| 293.15 | ||
| 267.16 | ||
| 307.18 | ||
| 267.16 | ||
| 297.19 | ||
| 253.13 | ||
| 233.14 | ||
| 279.13 | ||
| 267.16 | ||
| 253.13 | ||
| 297.19 | ||
| 285.15 | ||
| 271.12 | ||
| 233.14 | ||
| 285.15 |