Inhibition of beta lactamase NDM1 in Escherichia coli BAA-2452 assessed as potentiation of meropenem-induced antibacterial activity by measuring merop...

Basic Information

ID: ALA4374961

Type: Binding

Description: Inhibition of beta lactamase NDM1 in Escherichia coli BAA-2452 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 32 ug/ml)

Format: BAO_0000019

Organism: Escherichia coli

Strain: BAA-2452

Target:  Unchecked(ALA612545)

Document:  ALA4373692

Inhibition of beta lactamase NDM1 in Escherichia coli BAA-2452 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 32 ug/ml): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
300.30-1.52-1.52
217.290.630.63
307.18
177.03
267.16
307.18
267.16