Basic Information
ID: ALA4374962
Type: Binding
Description: Inhibition of beta lactamase NDM1 in Klebsiella pneumoniae 13249 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 64 ug/ml)
Format: BAO_0000357
Organism: Klebsiella pneumoniae
Strain: 13249
Target: Beta-lactamase NDM-1(ALA1667695)
Document: ALA4373692
Inhibition of beta lactamase NDM1 in Klebsiella pneumoniae 13249 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 64 ug/ml): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4374962
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.30 | -1.52 | -1.52 |
| 217.29 | 0.63 | 0.63 |
| 307.18 | ||
| 177.03 | ||
| 267.16 | ||
| 307.18 | ||
| 267.16 |