Basic Information
ID: ALA4374963
Type: Binding
Description: Inhibition of beta lactamase KPC-2 in Escherichia coli BAA-2340 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 4 ug/ml)
Format: BAO_0000357
Organism: Escherichia coli
Strain: BAA-2340
Target: Class A carbapenemase KPC-2(ALA5437)
Document: ALA4373692
Inhibition of beta lactamase KPC-2 in Escherichia coli BAA-2340 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 4 ug/ml): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4374963
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.30 | -1.52 | -1.52 |
| 217.29 | 0.63 | 0.63 |
| 307.18 | ||
| 177.03 | ||
| 267.16 | ||
| 307.18 | ||
| 267.16 |