Inhibition of beta lactamase KPC-2 in Escherichia coli 11119 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropen...

Basic Information

ID: ALA4374964

Type: Binding

Description: Inhibition of beta lactamase KPC-2 in Escherichia coli 11119 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 16 ug/ml)

Format: BAO_0000357

Organism: Escherichia coli

Strain: 11119

Target:  Class A carbapenemase KPC-2(ALA5437)

Document:  ALA4373692

Inhibition of beta lactamase KPC-2 in Escherichia coli 11119 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 16 ug/ml): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
300.30-1.52-1.52
217.290.630.63
307.18
177.03
267.16
307.18
267.16