Basic Information
ID: ALA4374981
Type: Binding
Description: Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 mins by ethidium bromide staining based gel electrophoresis method
Organism: Escherichia coli
Strain: ATCC 25922
Activity Charts
Bioactivity
Activity Types for Assay ALA4374981
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.35 | 1.58 | 1.58 |
| 396.92 | 4.96 | 4.96 |
| 444.54 | 3.97 | 3.97 |
| 447.51 | 3.60 | 3.60 |
| 426.52 | 4.11 | 4.11 |
| 432.50 | 4.10 | 4.10 |
| 415.50 | 3.36 | 3.36 |
| 438.50 | 3.02 | 3.02 |
| 446.53 | 4.41 | 4.41 |
| 448.50 | 3.08 | 3.08 |
| 446.53 | 4.41 | 4.41 |
| 432.50 | 4.10 | 4.10 |
| 486.57 | 2.42 | 2.42 |
| 415.49 | 3.93 | 3.93 |
| 428.54 | 4.27 | 4.27 |
| 449.49 | 2.47 | 2.47 |
| 428.54 | 4.27 | 4.27 |
| 414.51 | 3.97 | 3.97 |
| 449.49 | 2.47 | 2.47 |
| 448.50 | 3.08 | 3.08 |
| 432.50 | 4.10 | 4.10 |
| 448.95 | 4.62 | 4.62 |
| 400.48 | 3.58 | 3.58 |
| 467.48 | 2.61 | 2.61 |
| 446.48 | 3.63 | 3.63 |
| 374.49 | 3.18 | 3.18 |
| 418.54 | 3.69 | 3.69 |
| 426.52 | 4.11 | 4.11 |
| 439.52 | 3.84 | 3.84 |
| 437.52 | 2.60 | 2.60 |
| 428.49 | 3.49 | 3.49 |
| 448.95 | 4.62 | 4.62 |
| 444.54 | 3.97 | 3.97 |
| 448.95 | 4.62 | 4.62 |
| 496.51 | 3.22 | 3.22 |
| 454.57 | 3.74 | 3.74 |
| 457.58 | 4.03 | 4.03 |
| 485.47 | 2.75 | 2.75 |
| 428.54 | 3.99 | 3.99 |
| 439.52 | 3.84 | 3.84 |