Basic Information
ID: ALA4375049
Type: Binding
Description: Inhibition of human C-terminal His-tagged and N-terminal GST-tagged EGFR L858R/T790M/C797S triple mutant ( 668 to 1210 amino acids) expressed in baculovirus infected Sf9 insect cells using Poly(Glu,Tyr) 4:1 as substrate after 60 mins by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4373695
Inhibition of human C-terminal His-tagged and N-terminal GST-tagged EGFR L858R/T790M/C797S triple mutant ( 668 to 1210 amino acids) expressed in baculovirus infected Sf9 insect cells using Poly(Glu,Tyr) 4:1 as substrate after 60 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4375049
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.11 | 5.09 | 5.09 |
| 383.40 | 3.32 | 3.32 |
| 354.37 | 3.28 | 3.28 |
| 617.20 | 5.72 | 5.72 |
| 543.62 | 4.40 | 4.40 |
| 600.17 | 5.41 | 5.41 |
| 614.19 | 5.80 | 5.80 |
| 632.18 | 5.94 | 5.94 |
| 593.78 | 5.45 | 5.45 |
| 628.22 | 6.23 | 6.23 |
| 579.75 | 5.14 | 5.14 |
| 614.19 | 5.80 | 5.80 |
| 632.18 | 5.94 | 5.94 |
| 614.19 | 5.80 | 5.80 |
| 632.18 | 5.94 | 5.94 |
| 658.65 | 5.91 | 5.91 |
| 614.19 | 5.80 | 5.80 |