Basic Information
ID: ALA4375084
Type: Binding
Description: Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS cells after 2 hrs by fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Induced myeloid leukemia cell differentiation protein Mcl-1(ALA4361)
Document: ALA4373699
Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS cells after 2 hrs by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4375084
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.54 | 5.51 | 5.51 |
| 482.01 | 6.00 | 6.00 |
| 373.50 | 4.53 | 4.53 |
| 515.59 | 5.14 | 5.14 |
| 497.41 | 6.07 | 6.07 |
| 391.45 | 4.62 | 4.62 |
| 378.45 | 4.93 | 4.93 |
| 315.35 | 2.95 | 2.95 |
| 370.47 | 4.90 | 4.90 |
| 513.59 | 6.96 | 6.96 |
| 366.45 | 4.29 | 4.29 |
| 581.14 | 5.41 | 5.41 |
| 594.18 | 5.62 | 5.62 |
| 452.96 | 5.96 | 5.96 |
| 594.18 | 5.62 | 5.62 |
| 405.48 | 4.86 | 4.86 |
| 519.64 | 7.69 | 7.69 |
| 453.50 | 4.71 | 4.71 |
| 443.53 | 5.48 | 5.48 |
| 417.53 | 5.34 | 5.34 |
| 327.41 | 3.81 | 3.81 |
| 499.57 | 7.09 | 7.09 |
| 395.41 | 4.82 | 4.82 |
| 463.99 | 6.46 | 6.46 |
| 609.15 | 5.11 | 5.11 |
| 437.50 | 5.74 | 5.74 |
| 405.48 | 4.86 | 4.86 |
| 595.17 | 5.58 | 5.58 |
| 514.58 | 6.80 | 6.80 |
| 418.52 | 5.30 | 5.30 |
| 342.42 | 4.08 | 4.08 |
| 513.59 | 6.96 | 6.96 |
| 468.96 | 5.66 | 5.66 |
| 451.98 | 5.99 | 5.99 |
| 419.51 | 4.73 | 4.73 |
| 343.41 | 3.51 | 3.51 |
| 620.73 | 6.70 | 6.70 |
| 467.55 | 5.84 | 5.84 |
| 367.43 | 4.25 | 4.25 |
| 377.47 | 4.96 | 4.96 |
| 567.11 | 5.41 | 5.41 |
| 433.53 | 5.38 | 5.38 |
| 279.37 | 2.70 | 2.70 |
| 437.50 | 5.74 | 5.74 |
| 550.08 | 6.77 | 6.77 |
| 419.51 | 4.73 | 4.73 |
| 341.44 | 4.11 | 4.11 |