Basic Information
ID: ALA4375439
Type: Binding
Description: Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exchange preincubated for 10 mins followed by NaI-substituted PBS addition and measured by YFP-based fluorescence assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4375439
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.41 | 4.23 | 4.23 |
| 417.26 | 4.38 | 4.38 |
| 407.34 | 4.03 | 4.03 |
| 406.36 | 4.63 | 4.63 |
| 402.42 | 3.11 | 3.11 |
| 332.40 | 4.00 | 4.00 |
| 306.27 | 1.50 | 1.50 |
| 316.35 | 3.22 | 3.22 |
| 378.42 | 4.49 | 4.49 |
| 396.32 | 4.23 | 4.23 |
| 416.27 | 3.78 | 3.78 |
| 318.37 | 3.61 | 3.61 |
| 431.28 | 4.77 | 4.77 |
| 474.35 | 5.65 | 5.65 |
| 389.20 | 4.14 | 4.14 |
| 478.28 | 4.61 | 4.61 |
| 290.32 | 2.83 | 2.83 |
| 330.38 | 3.61 | 3.61 |
| 464.26 | 4.22 | 4.22 |
| 464.26 | 4.22 | 4.22 |
| 420.38 | 4.68 | 4.68 |
| 341.36 | 2.92 | 2.92 |
| 436.20 | 3.98 | 3.98 |
| 424.35 | 4.77 | 4.77 |
| 383.36 | 3.52 | 3.52 |
| 304.34 | 3.22 | 3.22 |
| 339.35 | 3.01 | 3.01 |
| 339.35 | 3.01 | 3.01 |
| 356.35 | 3.76 | 3.76 |
| 417.26 | 4.38 | 4.38 |
| 417.26 | 4.38 | 4.38 |
| 404.22 | 3.56 | 3.56 |
| 372.80 | 4.27 | 4.27 |
| 424.35 | 4.77 | 4.77 |
| 372.80 | 4.27 | 4.27 |
| 369.37 | 2.50 | 2.50 |
| 306.31 | 2.06 | 2.06 |
| 464.26 | 4.22 | 4.22 |
| 352.39 | 3.92 | 3.92 |
| 288.30 | 2.60 | 2.60 |
| 422.84 | 3.46 | 3.46 |
| 339.35 | 3.01 | 3.01 |
| 372.80 | 4.27 | 4.27 |
| 316.35 | 3.36 | 3.36 |
| 388.22 | 3.54 | 3.54 |