Basic Information
ID: ALA4375457
Type: Binding
Description: Allosteric modulation of human GFP-fused PK-tagged Gq-coupled NTR1 expressed in CHOK1 cells assessed as induction of NT (8 to 13) peptide-mediated beta-arrestin recruitment measured after 90 mins by pathhunter assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4375457
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.51 | 3.86 | 3.86 |
| 430.60 | 5.75 | 5.75 |
| 460.62 | 5.11 | 5.11 |
| 446.60 | 4.64 | 4.64 |
| 460.62 | 4.89 | 4.89 |
| 448.59 | 5.83 | 5.83 |
| 467.01 | 4.98 | 4.98 |
| 444.58 | 4.47 | 4.47 |
| 569.67 | 5.38 | 5.38 |
| 446.60 | 4.64 | 4.64 |
| 464.59 | 5.06 | 5.06 |
| 458.61 | 5.12 | 5.12 |
| 448.59 | 5.89 | 5.89 |
| 458.61 | 5.12 | 5.12 |
| 464.59 | 4.80 | 4.80 |
| 419.53 | 4.92 | 4.92 |
| 420.53 | 5.05 | 5.05 |
| 416.57 | 5.36 | 5.36 |
| 472.63 | 5.52 | 5.52 |
| 416.57 | 5.36 | 5.36 |
| 468.60 | 5.12 | 5.12 |
| 467.01 | 4.98 | 4.98 |
| 500.57 | 5.04 | 5.04 |
| 450.56 | 4.47 | 4.47 |
| 446.60 | 4.72 | 4.72 |
| 419.53 | 4.92 | 4.92 |
| 501.68 | 4.67 | 4.67 |
| 515.70 | 4.84 | 4.84 |
| 446.60 | 4.64 | 4.64 |
| 402.54 | 4.97 | 4.97 |
| 432.57 | 4.33 | 4.33 |
| 450.56 | 4.47 | 4.47 |
| 467.01 | 4.98 | 4.98 |
| 458.61 | 4.86 | 4.86 |
| 403.53 | 3.91 | 3.91 |
| 430.60 | 5.75 | 5.75 |
| 444.62 | 6.05 | 6.05 |
| 444.58 | 4.47 | 4.47 |
| 519.67 | 4.75 | 4.75 |
| 450.56 | 4.41 | 4.41 |
| 446.60 | 4.50 | 4.50 |
| 460.62 | 5.16 | 5.16 |
| 446.60 | 4.98 | 4.98 |