Assay Report Card

Basic Information

ID: ALA4375667

Type: Binding

Description: Inhibition of DprE1 in Mycolicibacterium smegmatis MC2 155 lysate assessed as reduction in epimerization of P[14C]RPP to DP[14C]A at 700 uM measured after 1.5 hrs in presence of NADH by TLC-based autoradiography

Organism: Mycolicibacterium smegmatis MC2 155

Subcellular Fraction: Lysate

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
447.485.105.10
477.505.115.11
470.486.216.21
477.505.115.11
500.506.226.22
441.515.635.63