Basic Information
ID: ALA4375670
Type: Binding
Description: Inhibition of DprE1 in Mycobacterium tuberculosis H37Rv assessed as accumulation of trehalose monomycolates at 10 times MIC measured after 24 hrs in presence of [14C]-acetate by TLC-based autoradiography
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA4375670
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.39 | 3.32 | 3.32 |
| 447.48 | 5.10 | 5.10 |
| 477.50 | 5.11 | 5.11 |
| 470.48 | 6.21 | 6.21 |
| 477.50 | 5.11 | 5.11 |
| 500.50 | 6.22 | 6.22 |
| 441.51 | 5.63 | 5.63 |