Assay Report Card

Basic Information

ID: ALA4375672

Type: Binding

Description: Inhibition of DprE1 in Mycobacterium tuberculosis H37Rv assessed as accumulation of trehalose monomycolates at 100 times MIC measured after 24 hrs in presence of [14C]-acetate by TLC-based autoradiography

Organism: Mycobacterium tuberculosis H37Rv

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
447.485.105.10
477.505.115.11
477.505.115.11
441.515.635.63