Basic Information
ID: ALA4375836
Type: Binding
Description: Inhibition of recombinant human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 DNA at 100 uM measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4373715
Inhibition of recombinant human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 DNA at 100 uM measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4375836
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.56 | 1.34 | 1.34 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 335.41 | 5.69 | 5.69 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |
| 335.41 | 5.69 | 5.69 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 335.41 | 5.69 | 5.69 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 335.41 | 5.69 | 5.69 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 385.85 | 6.05 | 6.05 |
| 351.41 | 5.40 | 5.40 |
| 351.41 | 5.40 | 5.40 |