Basic Information
ID: ALA4375995
Type: Binding
Description: Inhibition of TGFbeta1 receptor in TGFbeta1-stimulated Sprague-Dawley rat cardiac fibroblasts assessed as reduction in fibronectin expression at 10 uM measured after 12 hrs by Western blot analysis relative to control
Format: BAO_0000019
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: TGF-beta receptor type-1(ALA4523265)
Document: ALA4373718
Inhibition of TGFbeta1 receptor in TGFbeta1-stimulated Sprague-Dawley rat cardiac fibroblasts assessed as reduction in fibronectin expression at 10 uM measured after 12 hrs by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4375995
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.77 | 3.77 | 3.77 |
| 276.33 | 2.70 | 2.70 |
| 358.46 | 4.45 | 4.45 |
| 276.38 | 3.57 | 3.57 |
| 315.46 | 4.02 | 4.02 |
| 248.32 | 2.76 | 2.76 |
| 290.36 | 3.09 | 3.09 |
| 303.36 | 3.08 | 3.08 |
| 262.35 | 3.18 | 3.18 |
| 278.39 | 3.84 | 3.84 |
| 355.39 | 3.97 | 3.97 |
| 250.31 | 3.50 | 3.50 |
| 387.86 | 4.43 | 4.43 |
| 420.43 | 5.41 | 5.41 |
| 301.43 | 3.63 | 3.63 |
| 311.22 | 3.92 | 3.92 |
| 262.35 | 3.18 | 3.18 |
| 273.34 | 3.84 | 3.84 |
| 250.31 | 3.50 | 3.50 |
| 248.32 | 2.52 | 2.52 |
| 397.43 | 4.29 | 4.29 |
| 246.31 | 2.73 | 2.73 |
| 317.43 | 2.86 | 2.86 |
| 293.32 | 2.74 | 2.74 |
| 488.42 | 6.42 | 6.42 |
| 290.40 | 3.95 | 3.95 |
| 264.36 | 3.45 | 3.45 |
| 232.32 | 3.55 | 3.55 |
| 276.38 | 3.57 | 3.57 |
| 248.32 | 2.52 | 2.52 |
| 248.32 | 2.52 | 2.52 |