Basic Information
ID: ALA4376060
Type: Binding
Description: Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as thermal stabilization by sypro orange dye based thermal shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4376060
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.50 | 4.16 | 4.16 |
| 446.50 | 3.30 | 3.30 |
| 497.52 | 3.97 | 3.97 |
| 498.58 | 4.46 | 4.46 |
| 486.44 | 4.27 | 4.27 |
| 440.55 | 4.74 | 4.74 |
| 614.65 | 3.42 | 3.42 |
| 1052.10 | ||
| 392.16 | 3.45 | 3.45 |
| 612.69 | 2.22 | 2.22 |
| 550.64 | 3.86 | 3.86 |
| 452.58 | 4.79 | 4.79 |
| 623.71 | 5.06 | 5.06 |
| 285.26 | 2.05 | 2.05 |
| 373.42 | 5.22 | 5.22 |
| 455.50 | 5.45 | 5.45 |
| 463.62 | 5.90 | 5.90 |
| 1094.14 | ||
| 358.31 | 2.11 | 2.11 |