Basic Information
ID: ALA4376093
Type: Binding
Description: Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measured after 10 to 15 mins in presence of 0.01% Triton X-100 by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4376093
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.85 | 5.38 | 5.38 |
| 212.25 | 3.04 | 3.04 |
| 446.50 | 3.30 | 3.30 |
| 497.52 | 3.97 | 3.97 |
| 443.24 | 4.41 | 4.41 |
| 440.55 | 4.74 | 4.74 |
| 614.65 | 3.42 | 3.42 |
| 1052.10 | ||
| 550.64 | 3.86 | 3.86 |
| 452.58 | 4.79 | 4.79 |
| 623.71 | 5.06 | 5.06 |
| 463.62 | 5.90 | 5.90 |
| 1094.14 |