Basic Information
ID: ALA4376106
Type: Functional
Description: Neuroprotection in human amyloid beta (3 to 40 residues)-induced ICR mouse model of Alzheimer's disease assessed as inhibition of human amyloid beta N3pE-40 level in brain at 25 mg/kg, icv measured after 24 hrs by sandwich ELISA relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: ICR
Target: Mus musculus(ALA375)
Document: ALA4373720
Neuroprotection in human amyloid beta (3 to 40 residues)-induced ICR mouse model of Alzheimer's disease assessed as inhibition of human amyloid beta N3pE-40 level in brain at 25 mg/kg, icv measured after 24 hrs by sandwich ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376106
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.54 | 3.53 | 3.53 |
| 362.50 | 3.00 | 3.00 |
| 416.59 | 4.17 | 4.17 |
| 509.66 | 3.60 | 3.60 |
| 400.52 | 4.01 | 4.01 |
| 426.49 | 4.15 | 4.15 |
| 491.64 | 4.48 | 4.48 |
| 425.56 | 3.58 | 3.58 |
| 424.57 | 4.18 | 4.18 |
| 416.59 | 4.31 | 4.31 |
| 376.53 | 3.39 | 3.39 |
| 401.51 | 2.57 | 2.57 |
| 425.56 | 3.58 | 3.58 |
| 390.55 | 3.64 | 3.64 |
| 442.56 | 4.32 | 4.32 |
| 442.56 | 4.32 | 4.32 |
| 466.59 | 3.82 | 3.82 |
| 400.52 | 4.15 | 4.15 |
| 409.49 | 3.41 | 3.41 |
| 374.49 | 3.47 | 3.47 |
| 402.56 | 3.92 | 3.92 |
| 459.02 | 4.83 | 4.83 |
| 415.54 | 2.91 | 2.91 |
| 459.02 | 4.83 | 4.83 |