Basic Information
ID: ALA4376141
Type: Binding
Description: Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 380 residues) as substrate measured after 50 mins in presence of 70 nM [3H]-SAM by scintillation proximity assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4376141
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.66 | 1.99 | 1.99 |
| 438.54 | 0.37 | 0.37 |
| 490.66 | 3.65 | 3.65 |
| 501.68 | 4.21 | 4.21 |
| 488.64 | 3.43 | 3.43 |
| 520.69 | 2.16 | 2.16 |
| 505.67 | 3.12 | 3.12 |