Assay Report Card

Basic Information

ID: ALA4376273

Type: Binding

Description: Binding affinity to Pseudomonas aeruginosa tRNA (guanine(37)-N1)-methyltransferase (Leu5 to Asp25 residues) expressed in Escherichia coli BL21 (DE3) Rosetta T1R cells assessed as thermal stabilization of protein by measuring change in melting temperature at 0.1 mM by SYPRO orange based thermal shift assay

Organism: Pseudomonas aeruginosa

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
397.501.841.84
398.492.462.46
510.757.037.03
468.675.865.86
557.727.597.59
426.543.243.24
426.594.364.36
488.665.875.87
440.615.085.08
418.523.923.92
446.584.704.70