Basic Information
ID: ALA4376309
Type: Binding
Description: Inhibition of Pseudomonas aeruginosa tRNA (guanine(37)-N1)-methyltransferase (Leu5 to Asp25 residues) expressed in Escherichia coli BL21 (DE3) Rosetta T1R cells assessed as reduction in S-adenosyl-L-homocysteine production preincubated for 30 mins followed by 1.5 to 15 uM of tRNALeu(CAG) substrate and SAM addition and measured after 60 mins by MTase-Glo assay
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA4376309
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.59 | 4.36 | 4.36 |