Basic Information
ID: ALA4376310
Type: Binding
Description: Inhibition of Pseudomonas aeruginosa tRNA (guanine(37)-N1)-methyltransferase (Leu5 to Asp25 residues) expressed in Escherichia coli BL21 (DE3) Rosetta T1R cells assessed as reduction in S-adenosyl-L-homocysteine production up to 50 uM preincubated for 15 mins followed by 1.5 uM of tRNALeu(CAG) substrate and SAM addition and measured after 45 mins by MTase-Glo assay
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA4376310
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.49 | 2.46 | 2.46 |
| 510.75 | 7.03 | 7.03 |
| 468.67 | 5.86 | 5.86 |
| 426.54 | 3.24 | 3.24 |
| 488.66 | 5.87 | 5.87 |
| 440.61 | 5.08 | 5.08 |
| 418.52 | 3.92 | 3.92 |
| 446.58 | 4.70 | 4.70 |